GHRS: Higher Lows Volume Spike detected on 13 Mar 2026
All prices, scores, and news on this page reflect data available before market open on .
On 13 Mar 2026, our scan flagged GHRS as a higher lows volume spike setup scoring 77 out of 98 (Good tier), with a 71% win probability based on our historical pattern database and a 1.1 to 1 reward to risk ratio. This is a swing trade setup: win probability reflects a 10 trading day hold, not an intraday move. At $15.52, the conservative target is $16.32 with a stop at $13.79. A further breakout above resistance near $16.61 offers a larger move if momentum continues past the initial target.
Overall Score
77
of 98
Good
Win Probability
71%
High
Reward / Risk
1.1
: 1
$0.24 reward
$-0.21 risk
Swing Trading Plan
Entry
$15.52
Target
$16.32
Stop Loss
$13.79
Holding Period
Up to 10 trading days
Win Probability
71%
Current Setup
GHRS is forming a higher_lows_volume_spike pattern near $15.52 as the stock consolidates following the January 5, 2026 FDA clearance lifting the clinical hold on GH001. Structure score of 12.5/15 and volume ratio of 1.92x (432,036 shares vs. 224,709 avg) confirm accumulation. Key support sits at $13.60 with resistance at $16.61; the pattern sits 94.49% above its 52-week low but 20.45% below the 52-week high, indicating recovery from depressed valuations. RSI at 50.01 suggests neutral momentum—neither oversold nor overbought. The 70.62% win probability indicates solid historical pattern reliability.
Stock Context
On January 5, 2026, the FDA lifted the clinical hold on GHRS's GH001 investigational new drug application, enabling U.S. subject enrollment and progressing the company toward development alignment across major jurisdictions. The company expects to initiate its global pivotal Phase 3 program in 2026. In 2025, GHRS completed its Phase 2b trial and is now actively seeking FDA alignment on the design of its global Phase 3 pivotal program, with the Phase 2b trial meeting its primary endpoint with a placebo-adjusted MADRS reduction of -15.5 points at Day 8. Cash, cash equivalents and marketable securities were $280.7 million as of December 31, 2025. Nine analysts covering the stock have a consensus rating of "Strong Buy" with an average price target of $30.11, forecasting a 110.41% increase over the next year. Recent analyst actions through March 6, 2026 include Stifel Nicolaus and Canaccord Genuity reaffirming Buy ratings, with Citizens raising the price target to $42 from $39.
What to Expect
A successful breakout above $16.61 resistance would target the conservative measure move of $16.32—though limited upside suggests the measured target sits near the resistance itself, typical of consolidation patterns. Volume should remain elevated above the 1.92x ratio to confirm breakout legitimacy. The pattern invalidates decisively below the $13.60 support level, which would signal accumulation failure. The 70.62% win probability indicates that similar higher-lows patterns historically break upward more often than down, aligning with the biotech sector's event-driven dynamics heading into Phase 3 initiation catalysts.
Risk Factors
Recent positive clinical and earnings updates have often seen muted or negative next-day price reactions, suggesting a tendency toward downside or underreaction on good news, framing caution against extrapolating recent FDA clearance momentum. Clinical-stage risk remains elevated: Next quarter's EPS estimate is -$0.27, reflecting continued cash burn before any revenue generation. Phase 3 initiation in 2026 carries regulatory and execution risk; failure to replicate Phase 2b efficacy or safety would crater valuations. Small-cap status (market cap ~$848M) increases volatility sensitivity and float constraints. Beta of 0.87 suggests lower correlation to broad market but does not eliminate idiosyncratic biotech event risk. No imminent earnings catalyst listed, but regulatory updates on Phase 3 design alignment with the FDA or program initiation timing could trigger outsized moves. Limited historical data on mebufotenin in large pivotal trials represents unknown terrain.
Sources:
News Releases | GH Research
·
GH Research Announces FDA Lifts Clinical Hold on GH001, Clearing Path for Global Phase 3 Initiation in 2026 | GH Research
·
GH Research PLC to Provide Update on IND Application and Phase 3 Program for GH001 in Treatment-Resistant Depression | GHRS Stock News
·
GH Research to Announce IND Status for GH001 | GH Research
·
GH Research (GHRS) schedules IND, Phase 3 TRD update Jan. 5 | GHRS Stock News
·
GH Research to Announce IND Status for GH001
·
GHRS - Gh Research Plc Latest Stock News & Market Updates
·
GH Research stock rises on upcoming trial update (GHRS:NASDAQ) | Seeking Alpha
·
GH Research's IND Update and Phase 3 Program: A Catalyst for Long-Term Value Creation in Treatment-Resistant Depression
·
GH Research Reports Full Year 2025 Financial Results and Provides Business Update
·
GH Research PLC (GHRS) Stock Price, News, Quote & History - Yahoo Finance
·
Stock Quote & Chart | GH Research
·
Check out GH Research PLC's stock price (GHRS) in real time
·
GHRS: GH Research PLC Stock Price Quote - NASDAQ GM - Bloomberg
·
GH Research (GHRS) Stock Forecast, Price Targets and Analysts Predictions - TipRanks.com
·
GHRS Price Today: GH Research PLC Stock Price, Quote & Chart | MEXC
·
GH Research (GHRS) Stock Forecast & Analyst Price Targets
·
__symbol__ Stock Quote Price and Forecast | CNN
·
GH Research (GHRS) Stock Price, News & Analysis $GHRS
·
GH Research PLC (GHRS) Stock Price, Quote, News & Analysis | Seeking Alpha
How We Find and Score This Setup
We scan more than 6,000 NYSE and NASDAQ stocks every trading day and compare each detected pattern against a database of 370,000+ historical detections. Every setup is scored across three dimensions: Structure, Volume, and Breakout Readiness. Win probability is a calibrated estimate of how similar historical setups performed over the following 10 trading days. This is a swing trading tool built for multi-day holds. It is not built or tested for day trading.
Frequently Asked Questions
Is GHRS a good swing trade?
GHRS scored 77 out of 98 on our higher lows volume spike scan, with a 71% historical win probability over the standard 10 trading day hold. Good setup based on our systematic scoring.
What is the entry, target, and stop loss for this setup?
The setup's reference price is $15.52, with a conservative target of $16.32 and a stop loss at $13.79.
What would invalidate this higher lows volume spike setup?
A close below the stop loss at $13.79 would invalidate the setup and suggest the pattern has failed.
How is the win probability calculated?
Win probability is a calibrated estimate of how similar historical higher lows volume spike setups performed over the following 10 trading days, drawn from a database of 370,000+ historical pattern detections across 6,000+ NYSE and NASDAQ stocks.
Market & Sector Regime
Market
Neutral
-0.19
-1.0
0
+1.0
Health Care Sector
Neutral
-0.18
-1.0
0
+1.0
Other Patterns Detected Today
Bull Flag
58 days in pattern
Moderate
29.8
Overall Score
34
of 40
Pattern Quality
14
of 20
Setup
13
of 20
R/R
15
of 18
Context
Pattern Quality Score
12
of 15
Structure
10
of 13
Breakout
12
of 12
Volume
Recent Performance
Momentum & Trend
RSI (14)
50.0
Neutral
MACD Histogram
-0.02
Bearish
Bollinger Band Position
48.4%
Mid Zone
Volatility & Risk
20-Day Volatility
0.63
Very High
ATR %
6.3%
High
Beta
0.87
Market
Volume Analysis
Volume Ratio
1.92x
Very High
20-Day Avg Vol
225K
shares / day
Current Volume
432K
shares traded
Price Levels
52W High
$19.51
Resistance
$16.61
Target
$16.32
Current
$15.52
Stop Loss
$13.79
Support
$13.60
52W Low
$7.98
Disclaimer: This analysis is algorithmically generated for educational purposes only and does not constitute financial advice. Past pattern performance does not guarantee future results. Win probabilities are based on historical data across 370,000+ observations. Always conduct your own research and consult a qualified financial advisor. AI-assisted contextual analysis by Claude (Anthropic). Indicators reflect values at time of detection.